Innovative Methodology Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c

نویسندگان

  • Byoung Geun Han
  • Chuan-Ming Hao
  • Elena E. Tchekneva
  • Ying-Ying Wang
  • Chieh Allen Lee
  • Benyamin Ebrahim
  • Raymond C. Harris
  • Timothy S. Kern
  • David H. Wasserman
  • Matthew D. Breyer
  • Zhonghua Qi
چکیده

Byoung Geun Han, Chuan-Ming Hao, Elena E. Tchekneva, Ying-Ying Wang, Chieh Allen Lee, Benyamin Ebrahim, Raymond C. Harris, Timothy S. Kern, David H. Wasserman, Matthew D. Breyer, and Zhonghua Qi Department of Medicine, Vanderbilt University, Nashville, Tennessee; Department of Medicine, Case Western Reserve University, Cleveland, Ohio; Department of Molecular Physiology and Biophysics, Vanderbilt University; and The Mouse Metabolic Phenotyping Center, Vanderbilt University School of Medicine, Nashville, Tennessee

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Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c.

The present studies examined the relationship between fasting blood glucose and Hb A(1c) in C57BL/6J, DBA/2J, and KK/HlJ mice with and without diabetes mellitus. Daily averaged blood glucose levels based on continuous glucose monitoring and effects of 6-h vs. overnight fasting on blood glucose were determined. Daily averaged blood glucose levels were highly correlated with Hb A(1c), as determin...

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تاریخ انتشار 2008